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Mescaline

Also known as: buttons, mesc, san, san-pedro

Chemical structure of Mescaline

A psychedelic of the phenethylamine family. Found in psychedelic cacti that have long been used by peoples native to the Southwestern US and Mexico, including Peyote and San Pedro cacti, among others. Can be found as cactus pulp, as an extract from cacti, or as a synthetic substance created in a lab.

Dosage

Oral

Common: 200-300mg
Heavy: 500-700mg+
Light: 100-200mg
Strong: 300-500mg
Threshold: 100mg

NOTE: Doses are for Mescaline HCl

Duration

Onset: 60-180 minutes
Duration: 6-12 hours
After effects: 3-5 hours

Timeline

Onset
60-180 minutes
Peak
6-12 hours
After
3-5 hours
010h20h
Typical
Extended range

Effects

Euphoriaempathyinsightbrightened colourClosed/Open eye visualsenhanced tactile sensationmental/physical stimulationdecreased appetitepupil dilationrestlessnesschange in perceptionego softeningsweating/chillsmuscle tensionconfusioninsomnia

Drug Interactions

amt
Dangerous
lithium

There is a large number of reports indicating a high seizure and psychosis risk from this combination.

Dangerous
tramadol

This combination can cause seizures due to the lowering of the threshold by tramadol and the potential of mescaline to cause seziures.

Unsafe
2c t x
Caution
2c x
Caution
5 meo xxt

The 5-MeO class of tryptamines can be unpredictable in their interactions

Caution
amphetamines

The focus and anxiety caused by stimulants is magnified by psychedelics and results in an increased risk of thought loops

Caution
cannabis

Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics.

Caution
cocaine

The focus and anxiety caused by stimulants is magnified by psychedelics and results in an increased risk of thought loops

Caution
dox
Caution
maois
Caution
nbomes
Caution
alcohol
Low Risk & Decrease
benzodiazepines
Low Risk & Decrease
caffeine

High doses of caffeine are uncomfortable and this will be magnified by psychedelics

Low Risk & No Synergy
dextromethorphan
Low Risk & Synergy
dmt
Low Risk & Synergy
ghb/gbl
Low Risk & Decrease
ketamine
Low Risk & Synergy
lsd
Low Risk & Synergy
mdma
Low Risk & Synergy
mushrooms
Low Risk & Synergy
mxe
Low Risk & Synergy
nitrous
Low Risk & Synergy
opioids
Low Risk & No Synergy
pcp
Low Risk & Synergy
ssris
Low Risk & Decrease

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