← Back to all substances

LSD

Also known as: lsd-25, acid, cid, lucy

Chemical structure of LSD

LSD is a popular psychedelic with a relatively long history of use and research, and as such is known to be relatively safe despite its extremely high potency. It is the archetypical psychedelic to which all others are compared, and remains in popular usage.

Dosage

Oral

Common: 100-150ug
Heavy: 250ug+
Light: 50-100ug
Strong: 175-225ug

Note: These doses are for pure LSD, note that tabs are often rather a lot weaker than they are advertised.

Duration

Onset: 45-90 minutes
Duration: 9-14 hours
After effects: 12-24 hours

Timeline

Onset
45-90 minutes
Peak
9-14 hours
After
12-24 hours
019.8h1.6d
Typical
Extended range

Effects

visual distortionsa sense of childlike wonderbrightening of colorsracing thoughtshue shiftseuphoriaanxietyconfusion

Avoid

marijuana (Can potentiate effects)

Half-life

3-5 hours

Drug Interactions

lithium

There is a large number of reports indicating a high seizure and psychosis risk from this combination.

Dangerous
tramadol

Tramadol is well known to lower seizure threshold and psychedelics also cause occasional seizures.

Unsafe
amphetamines

Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences

Caution
cannabis

Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics.

Caution
cocaine

Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences

Caution
2c t x
Low Risk & Synergy
2c x
Low Risk & Synergy
5 meo xxt
Low Risk & Synergy
alcohol
Low Risk & Decrease
amt
Low Risk & Synergy
benzodiazepines
Low Risk & Decrease
caffeine
Low Risk & No Synergy
dextromethorphan
Low Risk & Synergy
dmt
Low Risk & Synergy
dox
Low Risk & Synergy
ghb/gbl
Low Risk & Decrease
ketamine
Low Risk & Synergy
maois
Low Risk & Decrease
mdma
Low Risk & Synergy
mescaline
Low Risk & Synergy
mushrooms
Low Risk & Synergy
mxe
Low Risk & Synergy
nbomes
Low Risk & Synergy
nitrous
Low Risk & Synergy
opioids
Low Risk & No Synergy
pcp
Low Risk & Synergy
ssris
Low Risk & Decrease

Community Notes

I really enjoyed this one

HoppingWolf93412/28/2025

Structure © Wikimedia