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A common hypnotic, sedative and anxiolytic benzodiazepine. High doses may cause amnesia and loss of inhibitions. Unusually, it is water soluble, and commonly used as a premedication for sedation as the solubility makes it better for IV use than other benzodiazepines.

Dosage

Insufflated

Common: 7-15mg
Light: 3-7mg
Strong: 15-25mg

Intramuscular

Common: 5-12mg
Light: 3-5mg
Strong: 12-25mg

Intravenous

Common: 5-10mg
Light: 2.5-5mg
Strong: 10-20mg

Oral

Common: 10-15mg
Light: 5-10mg
Strong: 15-30mg.

Rectal

Common: 7-15mg
Light: 3-7mg

Duration

Onset: undefined minutes
Duration: 4-8 hours
After effects: 1-12 hours

Timeline

Peak
4-8 hours
After
1-12 hours
010h20h
Typical
Extended range

Effects

AnxiolyticSedativeMuscle RelaxantAmnesiaDystaxiaHypnotic

Avoid

All other CNS depressants.

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