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Memantine
An NMDA-antagonist that if used recreationally can cause to a very prolonged "hole" lasting up to 16+ hours.
Dosage
Oral
Common: 20-40mg
Heavy: 40-80mg+
Light: 10-20mg
Duration
Onset: 30-90 minutes
Duration: 12-72 hours
After effects: 1-72 hours
Timeline
Onset
30-90 minutes
Peak
12-72 hours
After
1-72 hours
03.0d6.1d
Typical
Extended range