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Deoxymethoxetamine (DXME) is a novel dissociative from the arylcyclohexylamine family that emerged on the illicit market around 2020–2021. It has been identified as a new psychoactive substance and computationally predicted to possess addictive potential. Human pharmacological data remain limited, and effects show notable inter-individual variability.

Dosage

Oral

Common: 30-50mg
Heavy: 80mg+
Light: 15-25mg
Strong: 50-80mg

Duration

Onset: 30-90 minutes
Duration: 4-8 hours
After effects: 6-24 hours

Timeline

Onset
30-90 minutes
Peak
4-8 hours
After
6-24 hours
016.8h1.4d
Typical
Extended range

Effects

DissociationAnalgesiaEuphoriaCognitive impairmentSedationTime distortionImpaired coordinationConfusion

Avoid

Other dissociatives, alcohol, benzodiazepines, opioids, and other CNS depressants.

Half-life

Unknown.